The weight-loss shot: our plan ❤

A quick note for Yessi on what we want, why, and who to contact. Written Aug 19, 2026.

The short version

We want the real, FDA-approved shot (called Zepbound), not a cheaper "compounded" copy mixed by a pharmacy. It's a once-a-week shot you give yourself at home. It costs about $299–$449 a month paid out of pocket.

Why the brand-name one, not the cheap version

Online you'll see ads for $100–$200 a month. Those are almost always compounded tirzepatide, a pharmacy mixing the drug itself. It's the same idea, but:

Our thinking: we're injecting this into our body every week. For that, we want the exact same product a doctor's office or pharmacy would give, made by the actual manufacturer (Eli Lilly). Safety over saving a little money.

What to get

The product

Zepbound (tirzepatide) — single-dose vials

One shot per week, self-injected at home. You start low and build up over time so your body adjusts.

DoseCost / month (28-day supply)
2.5 mg (starting dose)$299
5 mg$399
7.5 mg – 15 mg$449

Ask for the vials (cheaper) rather than the pre-filled pens. Everyone starts at 2.5 mg for the first 4 weeks. One heads-up: for the higher doses ($449 tier), you have to reorder within 45 days each time or the price jumps, so keep the refills on schedule.

Three places to contact

All three sell the real brand-name Zepbound (not compounded). Start with the first one, it's the cheapest and comes straight from the maker.

BEST — straight from the manufacturer

1LillyDirect

Eli Lilly's own service (they make Zepbound). Cheapest, guaranteed authentic. You do a quick online medical visit, then they ship it.

lillydirect.lilly.com

2Ro (Ro Body)

Well-known telehealth company, nationwide, strong reviews. Handles the doctor visit and ships brand Zepbound. Charges a small membership on top.

ro.co/weight-loss

3LifeMD

Established weight-management telehealth program that also prescribes the brand version. Good backup if the first two have a wait.

lifemd.com/weight-management

Any of them will ask a few health questions (weight, height, medical history) before a doctor approves it. That's normal. They ship to Nevada.

Why not use our insurance?

We checked our Anthem plan directly. It does not cover Zepbound for weight loss (most plans exclude weight-loss shots). So paying cash through one of the three above is the route. The manufacturer price is already discounted for paying out of pocket.

This is a personal planning note, not medical advice. A licensed doctor at any of these services makes the final call on whether this shot is right and safe for us. Prices as of Aug 2026 and can change.